Volume 1 - Issue 4, November - December 2025

Ayurveda, one of the world’s oldest holistic systems of medicine, emphasizes the balance of body, mind, and spirit through personalized prevention and treatment strategies. Rooted in classical texts, Ayurveda encompasses a vast pharmacopeia of herbal, mineral, and herbo-mineral formulations, traditionally prepared through Panchabidha Kashaya Kalpana and its derived dosage forms such as Churna, Vati, Ghrita, Taila, Asava-Arishta, Avaleha, Bhasma, Pisti, Arka, and Malahara. While these formulations have demonstrated therapeutic potential for centuries, challenges related to standardization, quality control, bioavailability, stability, and safety have limited their global acceptance. The integration of modern technologies—particularly nanotechnology, artificial intelligence (AI), and digital health tools—offers transformative solutions to these challenges. Nanotechnology enhances bioavailability, targeted drug delivery, and shelf life of Ayurvedic medicines, with traditional Bhasmas increasingly recognized as nanoscale materials. AI contributes to drug discovery, formulation optimization, quality control, clinical decision support, and personalized medicine through Prakriti-based assessments. Digital platforms such as TKDL, AYUSH Research Portal, DHARA, and clinical software systems further strengthen research dissemination, standardization, and intellectual property protection. The convergence of traditional Ayurvedic wisdom with advanced scientific technologies promises improved efficacy, safety, and global relevance of Ayurvedic formulations, paving the way for evidence-based, personalized, and integrative healthcare in the future.