Big Data is increasingly recognized not merely as a technological tool but as a strategic driver of business innovation. This paper investigates how Big Data enables new business models, disrupts traditional practices, and generates measurable value across multiple industries. Comparative case studies of e-commerce (Amazon), entertainment (Netflix), automotive (Tesla), and finance (JPMorgan) illustrate how organizations leverage Big Data to drive innovation. This study identifies a research gap in linking Big Data initiatives to measurable innovation outcomes and proposes a solution framework to enhance strategic deployment. Future-level research directions include edge computing, federated learning, real-time analytics, and sustainable AI adoption.