Volume 2 - Issue 3, May - June 2026

Oral anticoagulation therapy, including vitamin K antagonists and direct oral anticoagulants, is essential for preventing thromboembolic events in hospitalized patients and during the transition to home. Despite its importance, therapeutic adherence remains suboptimal, particularly after discharge, increasing the risk of preventable complications and readmissions. Nurses, given their central role in patient education, medication reconciliation, and discharge coordination, are positioned to lead interventions that strengthen adherence and promote patient safety.This project evaluated the impact of a structured, nurse-led educational intervention on nursing staff’s knowledge, confidence, and educational practices related to anticoagulant management. A quasi-experimental pretest–posttest design without a control group was conducted in a metropolitan hospital in Puerto Rico with a convenience sample of thirty nurses. The intervention consisted of a 60-minute educational session integrating a didactic presentation, guided discussion, and the teach-back method. Significant improvements were observed in postintervention scores (p < 0.001), with increased knowledge, enhanced perceptions of nursing leadership, and greater confidence in educating anticoagulated patients. The findings demonstrate that structured educational interventions effectively strengthen clinical nursing leadership and standardize educational practices to improve therapeutic adherence to anticoagulants.

Rosemary Davila Gavino C, Dra. Erika Carrasquillo Meléndez,"Practice Change Project: Optimizing Therapeutic Adherence to Anticoagulants by Strengthening Nursing Leadership in the Hospital Setting" International Journal of Advanced Multidisciplinary Research and Educational Development, V2(3): Page(154-157) May-June 2026. ISSN: 3107-6513. www.ijamred.com. Published by Scientific and Academic Research Publishing.